New report of 71 studies show positive impact of ivermectin as part of COVID-19 treatment
The COVID-19 pandemic has led many people to learn more about their health, preexisting conditions, viral infections, and the healthcare system. They have learned about the FDA’s Emergency Use Authorization (EUA) authority with regards to drugs and treatments for various ailments including the coronavirus. They have also experienced various levels of government responding very differently in how they deal with the outbreak of this version of the SARS CoV-2.
At the core of all these issues is the body’s immune system, which regularly works to protect people. The immune system is a complex network of cells and proteins that defends the body against infection. The immune system keeps a record of every germ (microbe) it has ever defeated so it can recognise and destroy the microbe quickly if it enters the body again.
A new compilation of 71 studies with over 50,000 patients, shows the positive attributes of using the repurposed drug ivermectin. It has been safely used roughly 4 billion times, successfully fighting river blindness and other ailments around the world. The meta analysis using the most serious outcome shows 66 percent improvement with early treatment of COVID and 83 percent improvement when used as a prophylaxis against the COVID coronavirus.
The winter cold and flu season is now upon us, adding to people’s health concerns. Boosting your immune system and giving it the tools it needs to keep you healthy is at the core of the current pandemic health discussions.
Respiratory infections, including influenza, the COVID-19 virus and particularly pneumonia are a leading cause of death in people over 65 worldwide.
On the whole, your immune system does a remarkable job of defending you against disease-causing microorganisms. But sometimes it fails: a germ invades successfully and makes you sick. Is it possible to intervene in this process and boost your immune system? What if you improve your diet? How about taking certain vitamins or herbal preparations? Can you make other lifestyle changes in the hope of producing a near-perfect immune response?
The Frontline COVID Critical Care Alliance (FLCCC) is a group of healthcare professionals dedicated to fighting the SARS-Cov-2 virus and all its variants. They emerged seeking to use existing treatments in the care of their patients. They found certain treatments were successful in either preventing COVID sickness, or reducing the severity of the symptoms and duration of illness.
The FLCCC’s I-MASK+ protocol provides a wide range of ways to build your immune system as well as protecting yourself from COVID-19.
“These are all of the compounds, which have shown efficacy in the treatment of COVID-19,” said Dr. Pierre Kory at a November COVID-19 Summit in Florida. “Do you see the sheer number of trials and studies and compounds that have shown efficacy?”
The FLCCC Alliance is not opposed to vaccination, and furthermore supports policies such as mask wearing, social distancing, and hand hygiene to prevent the further spread of the SARS-CoV-2 virus. Our treatment proposals are designed, first of all, to mitigate the effects of the pandemic until it is overcome, and to allow for an earlier return to daily life.
The Omicron variant of the virus has more than 30 mutations. The current three FDA-approved vaccines offer uncertain levels of protection against this new variant, as breakthrough cases continue to rise in vaccinated people. This week, the FDA essentially stopped recommending the Johnson & Johnson vaccination due to serious side effects on a small but growing number of people. Therefore boosting your immune system becomes even more important.
The FLCCC clinicians are driven by their desire to save lives. They continually update their protocols based on clinical observations as well as the best studies of modes of prevention and treatment therapies for COVID-19.
The I-MASK+ Protocol is physiologic-based combination of treatment regimens developed by leaders in critical care medicine. All component medicines are FDA-approved, inexpensive, readily available and have been used for decades with well-established safety profiles. In October 2020, they added ivermectin as a core medication in the prevention and treatment of COVID-19.
Their immune boosting protocols and supportive therapy focuses on five treatments. Vitamin D, Vitamin C, Quercetin, Zinc, and melatonin.
- Vitamin D3 1,000–3,000 IU/day
- Vitamin C 500–1,000mg 2 x daily
- Quercetin 250 mg/day
- Zinc 30–40 mg/day (elemental zinc)
- Melatonin 6 mg before bedtime (causes drowsiness)
Their viral protection protocols are taking ivermectin twice weekly, and gargling with antiseptic mouthwash twice a day.
lvermectin
- Chronic Prevention – 0.2 mg/kg per dose (take with or after a meal) — twice a week for as long as disease risk is elevated in your community.
- Post COVID-19 Exposure Prevention – 0.4 mg/kg per dose (take with or after a meal) — one dose today, repeat after 48 hours.
Gargle mouthwash – 2 x daily – gargle (do not swallow) antiseptic mouthwash with cetylpyridinium chloride (e.g. ScopeTM, ActTM, CrestTM), 1 percent povidone/iodine solution or ListerineTM with essential oils.
Alternatively, they suggest Nigella Sativa (black cumin seed) at 40mg/kg daily, can be used if ivermectin is not available or added to ivermectin for optimal prevention.
Vitamin D appears to be one of many important components impacting your immune system. Many studies and healthcare professionals strongly recommend increasing the vitamin D in your system, especially as people remain indoors and get less sun exposure during the winter..
The quercetin appears to inhibit the SARS-CoV-2 virus from binding with the spike protein, which is how COVID-19 invades your body and spreads sickness.
Quercetin, a flavonoid with an excellent safety profile, has powerful antioxidant, anti-inflammatory, immunomodulatory and antiviral properties. It can potentially help in the early stage of SARS-CoV-2 viral infection to prevent disease development and progression. Its excellent safety profile allows widespread use in the early phase of the disease or when it is suspected, starting even before a confirmatory nasal swab is obtained. Quercetin acts as a free radical scavenger, and both in vitro and in vivo studies showed quercetin as a potent antioxidant.
There are some relevant cautions regarding quercetin. Due to a possible drug interaction between quercetin and ivermectin these drugs should be staggered (take one in the morning and one at night). Patients taking cyclosporin or tacrolimus should avoid quercetin. And for anyone with pre-existing thyroid disease or thyroidism, the lowest dose of quercetin should be used when taken as a preventative.
People who took zinc had symptoms go away about two days sooner, (compared to placebo), reports one recent study mentioned by Harvard Health. The estimated effect in preventing infection was modest: about one infection was prevented for every 20 people using zinc. More importantly, there was an 87 percent lower risk of severe symptoms among those taking zinc.
An Aug 2020 article in Women’s Health affirmed the melatonin recommendation:
“Melatonin is a special kind of ‘clean’ antioxidant, meaning that it’s able to protect cells without triggering production of free radicals. This appears to be important for immune cells, including phagocyte cells. Think of phagocyte immune cells as little Pac Men traveling through your bloodstream gobbling up pathogens. Studies show that melatonin helps to optimize phagocyte action.
“Children, who are much less likely to have severe COVID-19 symptoms, have as much as 10 times the amount of natural melatonin production as older adults. Now, there are also other factors that give children healthier immune function, but this may go a long way toward explaining why youth is so protective when it comes to coronavirus risk.”
Besides boosting your immune system, the FLCCC supports people taking antiviral precautions. These include gargling twice a day with antiseptic mouthwash and ivermectin.
The gargling makes sense because these cold and flu viruses enter your body primarily through your mouth or nose. If you can kill them before they incubate and travel down your air passageways into your lungs, you have a much greater chance of mild symptoms and better health outcomes.
Ivermectin
The “I” in the FLCCC’s recommended protocol is ivermectin. It has been safely used for decades, with roughly 4 billion doses administered globally. Yet there has been a huge battle by the government and the drug companies to keep citizens from using ivermectin.
“Many of those compounds are repurposed,” Kory said. “You know why? Because when this disease hit, there’s a lot of smart doctors, a lot of investigators who just started studying what they had available, instead of sitting around waiting till people turn blue.”
Nature magazine recently reported on repurposed drugs and compounds. “Given the high attrition rates, substantial costs and slow pace of new drug discovery and development, repurposing of ‘old’ drugs to treat both common and rare diseases is increasingly becoming an attractive proposition because it involves the use of de-risked compounds, with potentially lower overall development costs and shorter development timelines.”
There is a new report showing 71 studies demonstrate the effectiveness of ivermectin for both prevention and aiding patients in the recovery from COVID-19 sickness. The Meta analysis using the most serious outcome shows 66 percent and 83 percent improvement for early treatment and prophylaxis. The studies had over 50,000 patients.
Dr. Pierre Kory has been a leading advocate of using repurposed drugs and treatments in the battle against COVID-19. He shares a new metadata study with 71 studies and over 50,000 people. It shows excellent results for ivermectin in preventing sickness and improving recovery from COVID sickness. Video courtesy FLCCC Alliance
While many treatments have some level of efficacy, they do not replace vaccines and other measures to avoid infection, the analysis reports. Only 25 percent of ivermectin studies show zero events in the treatment arm. Multiple treatments are typically used in combination, which may be significantly more effective.
The greatest benefit appears to be an 83 percent improvement for people who took ivermectin prophylactically to improve their immune system’s chances of battling the virus should they encounter it.
The FLCCC Alliance originally recommended one dose per week of the ivermectin. Because of the highly contagious nature of the Delta variant of COVID-19, they increased their recommendation to twice per week, and suggested it be taken with a meal.
The amount you take is based on your weight – 0.2 mg per kg of weight. The conversion factor is 2.2 pounds per kg. A 132 pound person would take 12 mg; a 165 pound person would take 15 mg; and a 200 pound person would take an 18 mg dose.
The FLCCC is currently reviewing data regarding the Omicron variant to see if they need to adjust any of their treatments to offer better protection against this variant. Early reports indicate the symptoms are much more mild than the Delta variant. However it appears Omicron can be transmitted to others much more easily than either Delta or the original COVID-19 virus.
As always, they recommend you consult with your healthcare professional regarding any and all treatments, especially if you have preexisting conditions that add to your health risks.
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